Electrophys Feature Extraction Library

The Electrophys Feature Extract Library (eFEL) allows neuroscientists to automatically extract eFeatures from time series data recorded from neurons (both in vitro and in silico). Examples are the action potential width and amplitude in voltage traces recorded during whole-cell patch clamp experiments. The user of the library provides a set of traces and selects the eFeatures to be calculated. The library will then extract the requested eFeatures and return the values to the user.

The core of the library is written in C++, and a Python wrapper is included. You can automatically compile and install the library as a Python module.

The source code of the eFEL is located on github: openbraininstitute/eFEL

How to cite

When you use this eFEL software for your research, we ask you to cite it (this includes poster presentations) by referring to the following paper:

Mandge, D., Tuncel, A., Jaquier, A., Kilic, I., Damart, T., Markram, H., Van Geit, W., & Ranjan, R. (2026). eFEL: Electrophysiology feature extraction library. Bioinformatics, 42(6). https://doi.org/10.1093/bioinformatics/btag328

@article{10.1093/bioinformatics/btag328,
    author = {Mandge, Darshan and Tuncel, Anıl and Jaquier, Aurélien and Kilic, Ilkan and Damart, Tanguy and Markram, Henry and Van Geit, Werner and Ranjan, Rajnish},
    title = {eFEL: electrophysiology feature extraction library},
    journal = {Bioinformatics},
    volume = {42},
    number = {6},
    pages = {btag328},
    year = {2026},
    month = {06},
    issn = {1367-4811},
    doi = {10.1093/bioinformatics/btag328},
    url = {https://doi.org/10.1093/bioinformatics/btag328},
}

If you want to cite a particular version of eFEL, you can find the DOIs of all versions at: https://doi.org/10.5281/zenodo.19604220

Note: The earlier versions of code can be found in the Blue Brain Project eFEL: https://github.com/BlueBrain/eFEL, Zenodo: https://doi.org/10.5281/zenodo.14222078 and PyPI: https://pypi.org/project/efel/#history repositories.

Indices and tables

Source

index.rst